Two sample MR report
THEMIS2_Mature NK T Cell against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | -0.0064450 | 0.0739465 | 0.9333821 |
| Weighted median | 8 | 0.0225305 | 0.0076805 | 0.0033519 |
| Inverse variance weighted | 8 | 0.0234632 | 0.0063022 | 0.0001968 |
| Simple mode | 8 | 0.0222268 | 0.0110732 | 0.0847065 |
| Weighted mode | 8 | 0.0217830 | 0.0104807 | 0.0762652 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1297757 | 6 | 0.9999566 |
| Inverse variance weighted | 0.2945586 | 7 | 0.9999060 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0288802 | 0.071145 | 0.6988708 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002012 | 0 | TRUE | 0.1780663 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
